| Title |
Driver genes in non-small cell lung cancer: Characteristics, detection methods, and targeted therapies
|
|---|---|
| Published in |
Oncotarget, April 2017
|
| DOI | 10.18632/oncotarget.17016 |
| Pubmed ID | |
| Authors |
Qing-Ge Zhu, Shi-Ming Zhang, Xiao-Xiao Ding, Bing He, Hu-Qin Zhang |
| Abstract |
Lung cancer is one of the most common causes of cancer-related death in the world. The large number of lung cancer cases is non-small cell lung cancer (NSCLC), which approximately accounting for 75% of lung cancer. Over the past years, our comprehensive knowledge about the molecular biology of NSCLC has been rapidly enriching, which has promoted the discovery of driver genes in NSCLC and directed FDA-approved targeted therapies. Of course, the targeted therapies based on driver genes provide a more exact option for advanced non-small cell lung cancer, improving the survival rate of patients. Now, we will review the landscape of driver genes in NSCLC including the characteristics, detection methods, the application of target therapy and challenges. |
Mendeley readers
The data shown below were compiled from readership statistics for 151 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 151 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 23 | 15% |
| Researcher | 20 | 13% |
| Student > Ph. D. Student | 20 | 13% |
| Student > Bachelor | 19 | 13% |
| Student > Doctoral Student | 9 | 6% |
| Other | 21 | 14% |
| Unknown | 39 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 48 | 32% |
| Medicine and Dentistry | 25 | 17% |
| Agricultural and Biological Sciences | 14 | 9% |
| Chemistry | 4 | 3% |
| Engineering | 4 | 3% |
| Other | 10 | 7% |
| Unknown | 46 | 30% |