Watch an #OncotargetShort #video preview about Oncotarget's #PaperoftheWeek: "Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT." Read the full paper: https://t.co/xrddqviGlY #EMT #cancerresearch #openaccess
#FactFriday: Cells that have been stimulated over longer durations (10+ days) may render EMT irreversible and to become “locked” in a mesenchymal state. Read more in the #PaperoftheWeek: https://t.co/l732a0FSml #cancer #cancerresearch #medEd #OA https://
Oncotarget's #PaperoftheWeek features Figure 7: A seemingly irreversible MET at the population level. Starting with a population of mesenchymal cells on day 0 (all cells with very high value of the EMT inducer), the EMT inducer was with... Read the paper:
#PaperoftheWeek: In this 2020 paper, researchers discovered that one of the possible causes of resistance to EMT is stochastic partitioning of molecules during cell division. For their other proposed cause, read the full paper: https://t.co/WtbMxbHWt3 http
Oncotarget's #PaperoftheWeek features Figure 6: Reversibility of EMT starting from epithelial state (miR-200 = 17,000, mZEB = 50, ZEB = 10,000 molecules), a cell is treated by different time duration (5, 10, 20 arbitrary units [a.u], as mark... Read more:
Watch an #OncotargetShort #video preview about Oncotarget's #PaperoftheWeek: "Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT." Read the full paper: https://t.co/xrddqviGlY https://t.co/uKFk6Y04c1
The #PaperoftheWeek was authored by researchers from @RiceUniversity, @Northeastern and @iiscbangalore, and entitled: "Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT." https://t.co/xrddqviGlY #cancer #resea
Oncotarget's #PaperoftheWeek features Figure 5: Epigenetic feedback on inhibition of ZEB by GRHL2. (A) The bifurcation diagrams for core EMT circuit with/without epigenetic feedback on the inhibition of ZEB by GRHL2. Black curve rep... Read the full paper:
Figure 4 from Oncotarget's #PaperoftheWeek features: Epigenetic feedback on GRHL2 self-activation. (A) The bifurcation diagrams for core EMT circuit with/without epigenetic feedback on self-activation of GRHL2. Black curve denotes... Read the full paper: h
Figure 3 from Oncotarget's #PaperoftheWeek features: EMT decision-making network. (A) A core network regulating EMT via two mutually inhibition loops between miR-34 (miR-200) and SNAIL (ZEB). Signal I represents external EMT-inducin... Read the full paper:
Figure 2 from Oncotarget's #PaperoftheWeek features: GRHL2/ZEB1 axis correlates with EMT/MET across cancer types. (A) Pairwise Pearson’s correlation between different EMT and MET regulatory genes in the CCLE dataset. Pearson’s correlation val... Read more:
Figure 1 from Oncotarget's #PaperoftheWeek features: GRHL2 correlates with an epithelial phenotype. Scatter plots showing correlation of GRHL2 with EMT-TF ZEB1 and CDH1 (E-cadherin) in TCGA datasets and CCLE: (A) breast cancer, (B) colon... Read more: http
RT @mkjolly15: What controls the ability of cancer cells to switch states during metastasis? How reversible are these switches? Our @Oncot…
RT @mkjolly15: What controls the ability of cancer cells to switch states during metastasis? How reversible are these switches? Our @Oncot…
What controls the ability of cancer cells to switch states during metastasis? How reversible are these switches? Our @Oncotarget paper offers some answers. Here's an interview on our paper @BSSE_IISc @iiscbangalore @SMB_MathBiology https://t.co/Q8w59dBCoO
RT @mkjolly15: Excited to share our latest manuscript in @Oncotarget on how epigenetics and noise in cell division drives reversible/irreve…
RT @mkjolly15: Excited to share our latest manuscript in @Oncotarget on how epigenetics and noise in cell division drives reversible/irreve…
RT @mkjolly15: Excited to share our latest manuscript in @Oncotarget on how epigenetics and noise in cell division drives reversible/irreve…
RT @mkjolly15: Excited to share our latest manuscript in @Oncotarget on how epigenetics and noise in cell division drives reversible/irreve…
RT @mkjolly15: Excited to share our latest manuscript in @Oncotarget on how epigenetics and noise in cell division drives reversible/irreve…
RT @mkjolly15: Excited to share our latest manuscript in @Oncotarget on how epigenetics and noise in cell division drives reversible/irreve…
Excited to share our latest manuscript in @Oncotarget on how epigenetics and noise in cell division drives reversible/irreversible transitions in cancer cells https://t.co/BgefW3pPhL @BSSE_IISc @SMB_MathBiology #mathonco @Bio_IISc @iiscbangalore Thanks to