The goal of geroscience is life extension https://t.co/INt0HZuddz
@davidjglassMD As @mkaeberlein has detailed, healthspan is a nebulous term: https://t.co/xNf0FtPIXn @Blagosklonny has also done some interesting writing on this: https://t.co/xduXIPtPhv
@AgingBiology @JuliaB_fitness https://t.co/UBctReiAcQ Not one compound here will extend lifespan but because he’s suggested Q and D are easily accessible, people should take them for a 6.3% increase (where the above 👆🏼 got the idea) Absolutely pointless in
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
✨Do I have to deal with the ending? ....🌈 👉🏽"The end of #healthspan is subjective ...it’s not one disease but the sum of all diseases." https://t.co/wS8Yl7EY71
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
RT @Blagosklonny: Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the…
Effects on lifespan of Resveratrol, Rapamycin, NAD boosters, Metformin, Fisetin and many other drugs see rubrics in the middle of the article https://t.co/eTIM6gzaR8
@KristerKauppi Resveratrol data (and other) https://t.co/eTIM6gzaR8 among ref 35-37
RT @Blagosklonny: 2/2 quote: "Whatever off-target side effects anti-aging drugs may have, they will be avoided. Treatment is highly indivi…
2/2 quote: "Whatever off-target side effects anti-aging drugs may have, they will be avoided. Treatment is highly individual, because doses of rapamycin must be individual: the highest dose that does not cause side effect in a particular "patient.https://
@agingdoc1 This is how I define ANTI-AGING doses, side effects are markers that therapeutic doses are achieved, because they are individual, https://t.co/eTIM6gzaR8
@Blagosklonny from your paper: "drugs that fail to extend lifespan in mice will fail to extend lifespan in humans" https://t.co/RywOZF6Ttj Given the very high drug-failure rate, and obvious differences across species, why continue to assume only animal-d
To me it always seemed that this was due to the bad rep life extension has, as people tend to assume you’ll live longer and sicker if life extension occurs. In addition to other talking points. So it seems to be a shift in the argument (with the same end)
You are right and I disagree with Barzilai. Why should we die young and healthy, not from aging? The goal of geroscience is life extension due to health extension. https://t.co/eTIM6gzaR8
RT @Blagosklonny: Comparison of rapamycin and metformin discussed here in sections "rapamycin" "metformin" https://t.co/zHfNYbh4gM
@rhi0140 the list of drugs that affect lifespan https://t.co/52FeNrysW4
RT @Blagosklonny: Comparison of rapamycin and metformin discussed here in sections "rapamycin" "metformin" https://t.co/zHfNYbh4gM
RT @Blagosklonny: Comparison of rapamycin and metformin discussed here in sections "rapamycin" "metformin" https://t.co/zHfNYbh4gM
RT @Blagosklonny: Comparison of rapamycin and metformin discussed here in sections "rapamycin" "metformin" https://t.co/zHfNYbh4gM
RT @Blagosklonny: Comparison of rapamycin and metformin discussed here in sections "rapamycin" "metformin" https://t.co/zHfNYbh4gM
RT @Blagosklonny: Comparison of rapamycin and metformin discussed here in sections "rapamycin" "metformin" https://t.co/zHfNYbh4gM
RT @agingdoc1: The goal of geroscience is life extension https://t.co/kaiiDswpzk A research perspective by @Blagosklonny @Oncotarget -@ag…
If mTOR, metformin or rapa…… sounds Chinese to you, here is a good explanation https://t.co/hkxe2odnYp
Comparison of rapamycin and metformin discussed here in sections "rapamycin" "metformin" https://t.co/zHfNYbh4gM
RT @Oncotarget: #2021YearinReview: https://t.co/C99cdZ0S6O's most-viewed paper of 2021: #1: "The goal of geroscience is life extension" R…
#2021YearinReview: https://t.co/C99cdZ0S6O's most-viewed paper of 2021: #1: "The goal of geroscience is life extension" Read the full research perspective: https://t.co/1fVBHOsO8j #aging #geroscience #longevity #oncology #medEd #OA https://t.co/tRsvF6P5v
RT @RapamycinPress: Life extension by rapamycin vs other potential longevity drugs
RT @RapamycinPress: Life extension by rapamycin vs other potential longevity drugs
Life extension by rapamycin vs other potential longevity drugs
@AtlasShruggedGB @Boldizar I do rapamycin because other compounds do not extend lifespan in mammals. I review that here: https://t.co/AxDFlGRNRQ
@chydorina @InquilineKea @mold_time I provided an updated still unpublished list. In my papers, I explained the rationale for each agent. The latest https://t.co/AxDFlGActg
‘ The goal of #Geroscience is Life Extension - PubMed ‘ https://t.co/ztTFX9RA31
@chris_natale75 I wrote in my paper: "In one study, berberine extended lifespan in C57BL/6J male mice [81]. Of note, berberine inhibits the mTOR pathway in cell culture [82]. https://t.co/eTIM6gzaR8
@BlackATTR @kevinnbass only rapamycin prolongs life span (in 30 studies in mice and in all animals tested). Metformin just promises but does not deliver. See for references rapamycin and metformin sections: https://t.co/eTIM6gzaR8
RT @Blagosklonny: 2/2 But it's impossible to introduce genes in humans and then mate these humans, like it was done in mice. A drug is need…
RT @Blagosklonny: 2/2 But it's impossible to introduce genes in humans and then mate these humans, like it was done in mice. A drug is need…
RT @Blagosklonny: If a drug does not increase lifespan in mammals, there is no reason to think it would do so in humans https://t.co/eTIM6…
RT @5060fit: Smoking dramatically shortens lifespan. While smoking causes cancer, rapamycin prevents it, including smoke-caused lung cancer…
@Yu_Xuan_Lu @MattYousefzadeh @mkaeberlein @AgingSciTalks Rapamycin is widely used already, no studies are needed. See last section: how to proceed. There is only one rapalog - everolimus. https://t.co/eTIM6gzaR8
RT @Blagosklonny: If a drug does not increase lifespan in mammals, there is no reason to think it would do so in humans https://t.co/eTIM6…
If a drug does not increase lifespan in mammals, there is no reason to think it would do so in humans https://t.co/eTIM6gzaR8
RT @Blagosklonny: 2/2 But it's impossible to introduce genes in humans and then mate these humans, like it was done in mice. A drug is need…
RT @Blagosklonny: Rapamycin increases lifespan in all species tested. What else increases lifespan. Read here https://t.co/eTIM6gzaR8
RT @Blagosklonny: 2/2 But it's impossible to introduce genes in humans and then mate these humans, like it was done in mice. A drug is need…
RT @Blagosklonny: 2/2 But it's impossible to introduce genes in humans and then mate these humans, like it was done in mice. A drug is need…
2/2 But it's impossible to introduce genes in humans and then mate these humans, like it was done in mice. A drug is needed that extends lifespan by 30%. And there is only one drug that do that in mice: rapamycin https://t.co/eTIM6gzaR8
@NathanEqualsOne @DogAgingProject It's the one drug that actually seems like it might. https://t.co/yW27wnozyV
RT @Mangan150: Only a few drugs extend lifespan in mice and only one does it consistently. Some of them, alone or in combination, can be us…
RT @Mangan150: Only a few drugs extend lifespan in mice and only one does it consistently. Some of them, alone or in combination, can be us…
RT @Mangan150: Only a few drugs extend lifespan in mice and only one does it consistently. Some of them, alone or in combination, can be us…
RT @Mangan150: Only a few drugs extend lifespan in mice and only one does it consistently. Some of them, alone or in combination, can be us…
RT @Mangan150: Only a few drugs extend lifespan in mice and only one does it consistently. Some of them, alone or in combination, can be us…
RT @Mangan150: Only a few drugs extend lifespan in mice and only one does it consistently. Some of them, alone or in combination, can be us…
RT @Mangan150: Only a few drugs extend lifespan in mice and only one does it consistently. Some of them, alone or in combination, can be us…
RT @Mangan150: Only a few drugs extend lifespan in mice and only one does it consistently. Some of them, alone or in combination, can be us…
Only a few drugs extend lifespan in mice and only one does it consistently. Some of them, alone or in combination, can be used in humans, without further clinical trials. That's because they are already FDA approved for human use, and are safe. https://t.
RT @Blagosklonny: Rapamycin increases lifespan in all species tested. What else increases lifespan. Read here https://t.co/eTIM6gzaR8 http…
:)
RT @Blagosklonny: Rapamycin increases lifespan in all species tested. What else increases lifespan. Read here https://t.co/eTIM6gzaR8 http…
RT @Blagosklonny: Rapamycin increases lifespan in all species tested. What else increases lifespan. Read here https://t.co/eTIM6gzaR8
RT @Blagosklonny: Rapamycin increases lifespan in all species tested. What else increases lifespan. Read here https://t.co/eTIM6gzaR8 http…
RT @Blagosklonny: Rapamycin increases lifespan in all species tested. What else increases lifespan. Read here https://t.co/eTIM6gzaR8
RT @Blagosklonny: Rapamycin increases lifespan in all species tested. What else increases lifespan. Read here https://t.co/eTIM6gzaR8
Rapamycin increases lifespan in all species tested. What else increases lifespan. Read here https://t.co/eTIM6gzaR8
The goal of geroscience is life extension https://t.co/IHVFUg7dW6 https://t.co/Sw8Uba3Nwd
RT @Blagosklonny: @Orlando_uy Unfortunately this is misleading review. Alzheimer's disease is a human disease and studies were done mostly…