Oncotarget's #PaperoftheWeek features Figure 5: Metabolic analysis of PBMCs. (A) Oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) in Day 15 PBMCs samples by treatment arm demonstrates lower metabolic... Read the full paper: https:
#PaperoftheWeek: "An exploratory study of #metformin with or without #rapamycin as maintenance therapy after induction #chemotherapy in patients with metastatic pancreatic adenocarcinoma" Read the full #paper: https://t.co/nVzuxui92I #pancreaticcancer #on
Oncotarget's #PaperoftheWeek features Figure 4: High-dimensional flow cytometric analysis of PBMCs. (A) Gating tree demonstrating method for identification of immune cell subsets, and resultant t-distributed stochastic neighbor... Read the full paper: htt
RT @Oncotarget: Preclinical studies show that #metformin and #rapamycin combined demonstrate synergistic anti-tumor activity. In Oncotarget…
RT @Oncotarget: Preclinical studies show that #metformin and #rapamycin combined demonstrate synergistic anti-tumor activity. In Oncotarget…
Preclinical studies show that #metformin and #rapamycin combined demonstrate synergistic anti-tumor activity. In Oncotarget's #PaperoftheWeek, this therapeutic combination was explored in patients with metastatic #pancreaticcancer. Read the study results:
Oncotarget's #PaperoftheWeek features Figure 3: Kaplan-Meier estimates of (A) progression-free and (B) overall survival by treatment cohort. Read the full paper: https://t.co/wlcxLeQeBW https://t.co/0x4Hi9GhzD
Oncotarget's #PaperoftheWeek features Figure 2: Patient survival and tumor marker kinetics. (A) Swimmer plot of patient outcomes demonstrating time on treatment, time to progression, and survival. The end of the bar for subjects [...] Read the full paper:
Oncotarget's #PaperoftheWeek features Figure 1: Patient dispositions. "Thus 22 patients (11 in each arm) were treated per protocol." Read the full paper: https://t.co/wlcxLeQeBW https://t.co/cubMwzrik4
This was the publication, surprised I hadn’t posted it at the time: An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma https://t.co/F43Lssu
#pancreaticcancer Bever KM, Borazanci EH, Thompson EA, Durham JN, Pinero K, Jameson GS, Vrana A, Liu M, Wilt C, Wu AA, Fu W, Wang H, Yin Y, Leal JP, Jesus-Acosta A, Zheng L, Laheru DA, Von Hoff DD, Jaffee EM, Powell JD, Le DT An exploratory study of met…
RT @Blagosklonny: Important recent paper. Long term treatment with a combination of #metformin and #rapamycin, rapamycin (sirolimus) 4 mg o…
RT @Blagosklonny: Important recent paper. Long term treatment with a combination of #metformin and #rapamycin, rapamycin (sirolimus) 4 mg o…
RT @Blagosklonny: Important recent paper. Long term treatment with a combination of #metformin and #rapamycin, rapamycin (sirolimus) 4 mg o…
RT @Blagosklonny: Important recent paper. Long term treatment with a combination of #metformin and #rapamycin, rapamycin (sirolimus) 4 mg o…
RT @Blagosklonny: Important recent paper. Long term treatment with a combination of #metformin and #rapamycin, rapamycin (sirolimus) 4 mg o…
RT @Blagosklonny: Important recent paper. Long term treatment with a combination of #metformin and #rapamycin, rapamycin (sirolimus) 4 mg o…
RT @Blagosklonny: Important recent paper. Long term treatment with a combination of #metformin and #rapamycin, rapamycin (sirolimus) 4 mg o…
RT @Blagosklonny: Important recent paper. Long term treatment with a combination of #metformin and #rapamycin, rapamycin (sirolimus) 4 mg o…
RT @Blagosklonny: Important recent paper. Long term treatment with a combination of #metformin and #rapamycin, rapamycin (sirolimus) 4 mg o…
RT @Blagosklonny: Important recent paper. Long term treatment with a combination of #metformin and #rapamycin, rapamycin (sirolimus) 4 mg o…
Metformin with or without rapamycin for pancreatic cancer? Preliminary findings for sure but more reason to think about metformin in the context of cancer treatment. Is cancer, at least in part, a metabolic disease? https://t.co/LdIv6kIxPQ
RT @Blagosklonny: Important recent paper. Long term treatment with a combination of #metformin and #rapamycin, rapamycin (sirolimus) 4 mg o…
RT @Blagosklonny: Important recent paper. Long term treatment with a combination of #metformin and #rapamycin, rapamycin (sirolimus) 4 mg o…
Important recent paper. Long term treatment with a combination of #metformin and #rapamycin, rapamycin (sirolimus) 4 mg orally daily ! High chronic dose. And minimal side effects. No increase of blood glucose https://t.co/D1eysSOm8o